Monday 24 October 2016

Qualitative and Quantitative Analysis of Dan-Deng-Tong-Nao Capsules by HPLC-DAD-MS/MS

“Dan-Deng-Tong-Nao capsules” (DDTNCs) is a commonly used traditional Chinese formula medicine, which is prepared (extracted, purified and combined) from four commonly used Chinese herb drugs, including Radix Salvia miltiorrhiza, Radix Pueraria lobata, Erigeron breviscapus and Rhizoma chuanxiong.

Dan-Deng-Tong-Nao Capsules
DDTNCs have the ability of activating blood circulation to dissipate blood stasis, removing obstruction in the meridians and heart-nourishing effects. It was usually used for the treatment of apoplexy and the syndrome of apoplexy involving both collaterals and meridians caused by obstruction of collaterals by blood stasis.

Chemical constituents of the four component herbs of DDTNCs have been intensively studied. However, little is known about the chemical composition of DDTNCs, and the current analysis methods could not reflect the quality of it.

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