P-Chloro-m-cresol (PCMC) which is
also known as chlorocresol, is used as
an external germicide and bactericide agent. It has bactericidal activity
against Gram positive and Gram negative organisms, along with yeasts, moulds
and spores. It is also used as preservative for various pharmaceutical
preparations like cosmetics, lotions, tanning agents, and topical
corticosteroids. Other than that, it is also used in glues, paints and
varnishes, and leather goods.
Moreover, it is used widely in
eye drops, injections, shampoos and emulsions due to its disinfectant and
antifungal properties. Its antiseptic property makes it suitable for use in
heparin solutions, and in various creams
for skin care and dermatological care. Apart from that, it is reported as
potent activator of Ca2+ release mediated by ruthenium red/caffeine-sensitive
Ca2+ release channel in skeletal muscle sarcoplasmic reticulum.
Although PCMC is widely used in
pharmaceutical preparations but its effectiveness was reduced due to some
problems related to solubility and stability. Hence some alternative strategies
are needed which can modulate the physicochemical properties of PCMC. The
biofield treatment is an alternative strategy which is known to alter the
properties of living and non-living materials.
No comments:
Post a Comment