Pyrazole
containing natural products are very rare and such heterocycles are frequently
encountered in agrochemicals, pharmaceuticals, materials science, and synthetic
chemistry.
Compounds bearing
the pyrazole nucleus, in particular, have exhibited a wide spectrum of
therapeutic application and a plethora of drugs have progressed to the market,
such as lonazolac, fipronil, Viagra, celecoxib, and many others.
Pyrazoles also
constantly act as essential building blocks of ligands for transition metals,
supermolecules, and liquid crystals.
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