The Investigation of the Effect of Reduced and Microgravity Conditions on Single Bubble (Drop) Behavior Fixed on a Solid Surface in a Liquid

The study of the gas bubble (drop) behavior under reduced gravity and microgravity conditions may be used in the conceptual design of aircraft’s and space based gas-liquid management system.

It is very important to consider the changed gravity and microgravity conditions influence on the gas bubble (drop) behavior fixed on the solid surface, as this influence can be more strongly than other external forces action.

The main purpose of the present research to investigate the effect of reduced and microgravity conditions on single bubble (drop) behavior, fixed on the solid surface in the liquid.

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Thermodynamic Calculation of a Heat of First-Order Phase Transitions

A transition heat is the most important characteristics of first-order phase transitions. Black was first who discovered in 1762 that in the transfer of water to vapor, some quantity of heat is absorbed, which he termed the latent evaporation heat.

In spite of more than the two-hundred-year period of the heat transfer concept existence there are no analytical expressions relating the transition heat with other parameters of phase transitions.

For example, the fundamental "Physics Encyclopedia", articles devoted to the transition heat, evaporation heat, and so on, comprises no formulae but only tables of experimental data. One can also mention monographs which have no relationships except for the conventional definition of the transition heat λ=TΔS.

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Modern High Performance Liquid Chromatography

This year, our worldwide chromatography community will be celebrating 50 year anniversary of high performance liquid chromatography. 13 August 1966 Csaba Horvath and Seymour Lipsky are published in Nature their report about first high pressure separation of organic compounds on a self-packed ion exchange chromatographic column, entitled: “Use of Liquid Ion Exchange Chromatography for the Separation of Organic Compounds”.

Year latter was introduced first commercial HPLC instrument by Waters. To emphasize the major technological difference from typical at that time low pressure applications, HPLC meaning was “High Pressure Liquid Chromatography”.

Before 1966 liquid chromatography utilized either gravity flow or low pressure pumps for an eluent delivery. Typical applications there are protein separations using ion exchange and gel filtration, inorganic anion exchange chromatography and normal phase separations of various organic substances using self – packed silica columns.

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Mixed Matrix Membranes for Adsorption Application

Mixed matrix membrane (MMM), a currently popular research field, is a type of membrane formed by incorporating fillers in polymer matrix. Its preparation procedures mainly involve with only blending and phase inversion.

According to its structure, MMM can typically be divided into two categories. The first one is with a dense structure, mostly developed for the applications in gas separation, pervaporation, fuel cell, and so on. The fillers employed for improving the MMM performance in this category are usually inorganic nanomaterials (zeolite, carbon nanotube, metal organic framework, etc.) with specific features (shape, pore size, surface interaction, etc.).

The other category is with a porous structure, specially designed for adsorption purpose. Micro-to-nano-size particles with functionality are regularly adopted as the fillers for this kind of MMM to provide the adsorptivity with target solutes.

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Modern High Performance Liquid Chromatography and HPLC 2016 International Symposium

This year, our worldwide chromatography community will be celebrating 50 year anniversary of high performance liquid chromatography. 13 August 1966 Csaba Horvath and Seymour Lipsky are published in Nature their report about first high pressure separation of organic compounds on a self-packed ion exchange chromatographic column, entitled. “Use of Liquid Ion Exchange Chromatography for the Separation of Organic Compounds”.

Year latter was introduced first commercial HPLC instrument by Waters. To emphasize the major technological difference from typical at that time low pressure applications, HPLC meaning was “High Pressure Liquid Chromatography”.

Before 1966 liquid chromatography utilized either gravity flow or low pressure pumps for an eluent delivery. Typical applications there are protein separations using ion exchange and gel filtration, inorganic anion exchange chromatography and normal phase separations of various organic substances using self – packed silica columns. Isolation range was varied from analytical to preparative.

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Thermodynamic Calculation of a Heat of First-Order Phase Transitions

A transition heat is the most important characteristics of first-order phase transitions. Black was first who discovered in 1762 that in the transfer of water to vapor, some quantity of heat is absorbed, which he termed the latent evaporation heat. In spite of more than the two-hundred-year period of the heat transfer concept existence there are no analytical expressions relating the transition heat with other parameters of phase transitions.

For example, the fundamental "Physics Encyclopedia", articles devoted to the transition heat, evaporation heat, and so on, comprises no formulae but only tables of experimental data. One can also mention monographs which have no relationships except for the conventional definition of the transition heat λ=TΔS.

Hence, obtaining the relationships between the transition heat and other parameters of first-order phase transitions will be a substantial contribution into the theory of first-order phase transitions.  The conventional expression for a transition heat λ=TΔS has two substantial drawbacks. First, in some phase transitions, for example, in evaporation, not only entropy changes but a system does the work, which can only be supplied by an external source of heat.

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Features of N-Glycosylation of Immunoglobulins from Knockout Pig Models

For the first time, the N-glycosylation patterns of immunoglobulin G (IgGs) isolated from the serum of two varieties of knockout pigs (lacking N-glycolylneuraminic acid (Neu5Gc) and/or α 1,3 galactose) were examined for the presence of potential glycan xenoantigens and compared to N-glycosylation patterns obtained for wild-type (WT) pig IgGs.

Glycopeptide analysis was chosen over glycan release, as protein-A eluates from pig serum may contain IgA and IgM as shown previously. The experiments focused on the analysis of tryptic glycopeptides EEQFNSTYR and AEQFNSTYR from IgGs, and excluded IgA and IgM, in which N-glycosylated peptides have different sequences and masses. WT pig IgG glycopeptides showed the presence of N-glycolylneuraminic acid (Neu5Gc) and absence of N-acetylneuraminic acid (Neu5Ac). Released glycans from the protein-A eluate, however, showed the presence of both types of sialic acids, allowing Neu5Ac to be attributed to IgA and/or IgM.

The WT IgG samples also showed the presence of glycans that could by composition have been α-galactosylated, but treatments with α- and β-galactosidases produced inconclusive results as to the linkage nature of the terminal Gal residues. Single knockout (α-Gal transferase) pig IgG was shown to contain Neu5Gc residues, and there was a definite absence of α-Gal.