Monday, 5 June 2017

Gas Chromatographic Assessment of Residual Solvents Present in Excipient-Benzyl Alcohol

This article describes a simple and rapid gas chromatographic method for identification of residual solvents present in benzyl alcohol. Benzyl alcohol is used in foods and pharmaceutical products.
Excipient-Benzyl Alcohol

The organic solvents such as benzene, chlorobenzene and toluene are frequently used in manufacturing of benzyl alcohol. Even after such manufacturing process, some solvents still remain in small quantities.

Method for the quantification of residual solvents present in benzyl alcohol was done by gas chromatography with flame ionization detector and utilizes the Agilent 7700 with FID (DB-624, 30 m × 0.53 mm, 3 μ) capillary column, nitrogen as carrier gas with a flow rate of 2.5 ml mn-1.

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